1992~1998 College of Medicine, Seoul National University (M.D.)
1999~2001 College of Medicine, Seoul National University (M.S. / Biochemistry) - Supervisor : Jeong-Sun Seo
2001~2007 College of Medicine, Seoul National University (Ph.D. / Biochemistry) - Supervisor : Jeong-Sun Seo
WORK EXPERIENCE
2009~2013 : Research Associate, Harvard Medical School
2013~2016 : Senior Research, The Jackson Laboratory for Genomic Medicine
2016~Present : Assistant/Associate Professor, GIST
2015.09~Present : Chief Technology Officer (CTO), Genome & Company
REPRESENTATIVE_PUBLICATIONS
You can find all published articles at researchgate.net : https://www.researchgate.net/profile/Hansoo-Park
IF>10 ; According to JCR IF, Year 2023 (1-14)
1st or corresponding author (1-28)
1. Kim G, Yoon Y, Park JH, Park JW, Noh MG, Kim H, et al. Bifidobacterial carbohydrate/nucleoside metabolism enhances oxidative phosphorylation in white adipose tissue to protect against diet-induced obesity. Microbiome. 2022;10(1):188. Epub 20221104. doi: 10.1186/s40168-022-01374-0. PubMed PMID: 36333752; PubMed Central PMCID: PMC9635107.
2. Park J, Lutz SM, Choi S, Lee S, Park SC, Kim K, et al. Multi-omics analyses implicate EARS2 in the pathogenesis of atopic dermatitis. Allergy. 2021;76(8):2602-4. Epub 20210604. doi: 10.1111/all.14837. PubMed PMID: 33792063.
3. Noh MG, Yoon Y, Kim G, Kim H, Lee E, Kim Y, et al. Practical prediction model of the clinical response to programmed death-ligand 1 inhibitors in advanced gastric cancer. Exp Mol Med. 2021;53(2):223-34. Epub 20210205. doi: 10.1038/s12276-021-00559-1. PubMed PMID: 33547412; PubMed Central PMCID: PMC8080676.
4. Na D, Chae J, Cho SY, Kang W, Lee A, Min S, et al. Predictive biomarkers for 5-fluorouracil and oxaliplatin-based chemotherapy in gastric cancers via profiling of patient-derived xenografts. Nat Commun. 2021;12(1):4840. Epub 20210810. doi: 10.1038/s41467-021-25122-4. PubMed PMID: 34376661; PubMed Central PMCID: PMC8355375.
5. Lee SH, Cho SY, Yoon Y, Park C, Sohn J, Jeong JJ, et al. Bifidobacterium bifidum strains synergize with immune checkpoint inhibitors to reduce tumour burden in mice. Nat Microbiol. 2021;6(3):277-88. Epub 20210111. doi: 10.1038/s41564-020-00831-6. PubMed PMID: 33432149.
6. Yoon Y, Kim G, Noh MG, Park JH, Jang M, Fang S, et al. Lactobacillus fermentum promotes adipose tissue oxidative phosphorylation to protect against diet-induced obesity. Exp Mol Med. 2020;52(9):1574-86. Epub 20200911. doi: 10.1038/s12276-020-00502-w. PubMed PMID: 32917958; PubMed Central PMCID: PMC8080655.
7. Cho SY, Sung CO, Chae J, Lee J, Na D, Kang W, et al. Alterations in the Rho pathway contribute to Epstein-Barr virus-induced lymphomagenesis in immunosuppressed environments. Blood. 2018;131(17):1931-41. Epub 20180223. doi: 10.1182/blood-2017-07-797209. PubMed PMID: 29475961; PubMed Central PMCID: PMC5921963.
8. Cho SY, Park C, Na D, Han JY, Lee J, Park OK, et al. High prevalence of TP53 mutations is associated with poor survival and an EMT signature in gliosarcoma patients. Exp Mol Med. 2017;49(4):e317. Epub 20170414. doi: 10.1038/emm.2017.9. PubMed PMID: 28408749; PubMed Central PMCID: PMC5420801.
9. Cho SY, Kang W, Han JY, Min S, Kang J, Lee A, et al. An Integrative Approach to Precision Cancer Medicine Using Patient-Derived Xenografts. Mol Cells. 2016;39(2):77-86. Epub 20160202. doi: 10.14348/molcells.2016.2350. PubMed PMID: 26831452; PubMed Central PMCID: PMC4757806.
10. Park H, Cho SY, Kim H, Na D, Han JY, Chae J, et al. Genomic alterations in BCL2L1 and DLC1 contribute to drug sensitivity in gastric cancer. Proc Natl Acad Sci U S A. 2015;112(40):12492-7. Epub 20150923. doi: 10.1073/pnas.1507491112. PubMed PMID: 26401016; PubMed Central PMCID: PMC4603466.
11. Ju YS, Kim JI, Kim S, Hong D, Park H, Shin JY, et al. Extensive genomic and transcriptional diversity identified through massively parallel DNA and RNA sequencing of eighteen Korean individuals. Nat Genet. 2011;43(8):745-52. Epub 20110703. doi: 10.1038/ng.872. PubMed PMID: 21725310.
12. Lee JE, Park H, Ju YS, Kwak M, Kim JI, Oh HY, et al. Higher mitochondrial DNA copy number is associated with lower prevalence of microalbuminuria. Exp Mol Med. 2009;41(4):253-8. doi: 10.3858/emm.2009.41.4.028. PubMed PMID: 19299914; PubMed Central PMCID: PMC2679230.
13. Kim JI, Ju YS, Park H, Kim S, Lee S, Yi JH, et al. A highly annotated whole-genome sequence of a Korean individual. Nature. 2009;460(7258):1011-5. Epub 20090708. doi: 10.1038/nature08211. PubMed PMID: 19587683; PubMed Central PMCID: PMC2860965.
14. Gombojav B, Park H, Kim JI, Ju YS, Sung J, Cho SI, et al. Heritability and linkage study on heart rates in a Mongolian population. Exp Mol Med. 2008;40(5):558-64. doi: 10.3858/emm.2008.40.5.558. PubMed PMID: 18985014; PubMed Central PMCID: PMC2679351.
15. Won EJ, Jang HH, Park H, Kim SJ. A Potential Predictive Role of the Scalp Microbiome Profiling in Patients with Alopecia Areata: Staphylococcus caprae, Corynebacterium, and Cutibacterium Species. Microorganisms. 2022;10(5). Epub 20220421. doi: 10.3390/microorganisms10050864. PubMed PMID: 35630309; PubMed Central PMCID: PMC9148078.
16. Min K, Kim HT, Lee EH, Park H, Ha YS. Bacteria for Treatment: Microbiome in Bladder Cancer. Biomedicines. 2022;10(8). Epub 20220725. doi: 10.3390/biomedicines10081783. PubMed PMID: 35892683; PubMed Central PMCID: PMC9332069.
17. Lee E, Min K, Ahn H, Jeon BN, Park S, Yun C, et al. Potential Therapeutic Skin Microbiomes Suppressing Staphylococcus aureus-Derived Immune Responses and Upregulating Skin Barrier Function-Related Genes via the AhR Signaling Pathway. Int J Mol Sci. 2022;23(17). Epub 20220823. doi: 10.3390/ijms23179551. PubMed PMID: 36076953; PubMed Central PMCID: PMC9455615.
18. Lee E, Ahn H, Park S, Kim G, Kim H, Noh MG, et al. Staphylococcus epidermidis WF2R11 Suppresses PM(2.5)-Mediated Activation of the Aryl Hydrocarbon Receptor in HaCaT Keratinocytes. Probiotics Antimicrob Proteins. 2022;14(5):915-33. Epub 20220621. doi: 10.1007/s12602-022-09922-8. PubMed PMID: 35727505; PubMed Central PMCID: PMC9474527.
19. Kim S, Kim Y, Lee S, Kim Y, Jeon B, Kim H, et al. Live Biotherapeutic Lactococcus lactis GEN3013 Enhances Antitumor Efficacy of Cancer Treatment via Modulation of Cancer Progression and Immune System. Cancers (Basel). 2022;14(17). Epub 20220823. doi: 10.3390/cancers14174083. PubMed PMID: 36077619; PubMed Central PMCID: PMC9455052.
20. Han Y, Kim G, Ahn E, Jung S, Jung Y, Kim Y, et al. Integrated metagenomics and metabolomics analysis illustrates the systemic impact of the gut microbiota on host metabolism after bariatric surgery. Diabetes Obes Metab. 2022;24(7):1224-34. Epub 20220324. doi: 10.1111/dom.14689. PubMed PMID: 35257467; PubMed Central PMCID: PMC9313881.
21. Ahn H, Min K, Lee E, Kim H, Kim S, Kim Y, et al. Whole-Transcriptome Sequencing Reveals Characteristics of Cancer Microbiome in Korean Patients with GI Tract Cancer: Fusobacterium nucleatum as a Therapeutic Target. Microorganisms. 2022;10(10). Epub 20220923. doi: 10.3390/microorganisms10101896. PubMed PMID: 36296174; PubMed Central PMCID: PMC9610011.
22. Yoon Y, Kim G, Jeon BN, Fang S, Park H. Bifidobacterium Strain-Specific Enhances the Efficacy of Cancer Therapeutics in Tumor-Bearing Mice. Cancers (Basel). 2021;13(5). Epub 20210225. doi: 10.3390/cancers13050957. PubMed PMID: 33668827; PubMed Central PMCID: PMC7956760.
23. Son M, Noh MG, Lee JH, Seo J, Park H, Yang S. Effect of aspirin on coronavirus disease 2019: A nationwide case-control study in South Korea. Medicine (Baltimore). 2021;100(30):e26670. doi: 10.1097/md.0000000000026670. PubMed PMID: 34397693; PubMed Central PMCID: PMC8322539.
24. Noh MG, Kim SS, Kim YJ, Jung TY, Jung S, Rhee JH, et al. Evolution of the Tumor Microenvironment toward Immune-Suppressive Seclusion during Brain Metastasis of Breast Cancer: Implications for Targeted Therapy. Cancers (Basel). 2021;13(19). Epub 20210929. doi: 10.3390/cancers13194895. PubMed PMID: 34638378; PubMed Central PMCID: PMC8507988.
25. Kim G, Kim M, Kim M, Park C, Yoon Y, Lim DH, et al. Spermidine-induced recovery of human dermal structure and barrier function by skin microbiome. Commun Biol. 2021;4(1):231. Epub 20210219. doi: 10.1038/s42003-020-01619-4. PubMed PMID: 33608630; PubMed Central PMCID: PMC7895926.
26. Kim E, Ahn H, Park H. A review on the role of gut microbiota in immune checkpoint blockade therapy for cancer. Mamm Genome. 2021;32(4):223-31. Epub 20210330. doi: 10.1007/s00335-021-09867-3. PubMed PMID: 33783613; PubMed Central PMCID: PMC8295158.
27. Park H, Lee S, Kim HJ, Ju YS, Shin JY, Hong D, et al. Comprehensive genomic analyses associate UGT8 variants with musical ability in a Mongolian population. J Med Genet. 2012;49(12):747-52. Epub 20121101. doi: 10.1136/jmedgenet-2012-101209. PubMed PMID: 23118445; PubMed Central PMCID: PMC3512346.
28. Ju YS, Park H, Lee MK, Kim JI, Sung J, Cho SI, et al. A genome-wide Asian genetic map and ethnic comparison: the GENDISCAN study. BMC Genomics. 2008;9:554. Epub 20081125. doi: 10.1186/1471-2164-9-554. PubMed PMID: 19025666; PubMed Central PMCID: PMC2612022.
