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Laboratory of Genomic Medicine

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[Molecular Cancer] Genome-wide CRISPR screening identifies tyrosylprotein sulfotransferase-2 as a target for augmenting anti-PD1 efficacy
  • AuthorYumi Oh, Sujeong Kim, Yunjae Kim, Hyun Kim, Dongjun Jang, Seungjae Shin, Soo-Jin Lee, Jiwon Kim, Sang Eun Lee, Jaeik Oh, Yoojin Yang, Dohee Kim, Hae Rim Jung, Sangjin Kim, Jihui Kim, Kyungchan Min, Beomki Cho, Hoseok Seo, Dohyun Han, Hansoo Park, Sung-Yup Cho
  • Year2024.08.
  • Sourcehttps://doi.org/10.1186/s12943-024-02068-x

[Cell Host & Microbe] Fecal microbiota transplantation improves anti-PD-1 inhibitor efficacy in unresectable or metastatic solid cancers refractory to anti-PD-1 inhibitor
  • AuthorYunjae Kim, Gihyeon Kim, Sujeong Kim, Beomki Cho, Sang-Yeob Kim, Eun-Ju Do, Dong-Jun Bae, Seungil Kim, Mi-Na Kweon, Joon Seon Song, Sang Hyoung Park, Sung Wook Hwang, Mi-Na Kim, Yeongmin Kim, Kyungchan Min, Sung-Han Kim, Mark D. Adams, Charles Lee, Hansoo Park, Sook Ryun Park
  • Year2024.07.
  • Sourcehttps://doi.org/10.1016/j.chom.2024.06.010

[Advanced Science] Intracellular Adhesion Molecule-1 Improves Responsiveness to Immune Checkpoint Inhibitor by Activating CD8+ T Cells
  • AuthorSe-Hoon Lee, Yeongmin Kim, Bu-Nam Jeon, Gihyeon Kim, Jinyoung Sohn, Youngmin Yoon, Sujeong Kim, Yunjae Kim, Hyemin Kim, Hongui Cha, Na-Eun Lee, Hyunsuk Yang, Joo-Yeon Chung, A-Reum Jeong, Yun Yeon Kim, Sang Gyun Kim, Yeonhee Seo, Sehhoon Park, Hyun Ae Jung, Jong-Mu Sun, Jin Seok Ahn, Myung-Ju Ahn, Hansoo Park, Kyoung Wan Yoon
  • Year2023.04.
  • Sourcehttps://doi.org/10.1002/advs.202204378

Microbiome - Bifidobacterial carbohydrate/ nucleoside metabolism enhances oxidative phosphorylation in white adipose tissue to protect against diet‑induced obesity
  • AuthorGihyeon Kim, Youngmin Yoon, Jin Ho Park, Jae Won Park, Myung‑guin Noh, Hyun Kim, Changho Park, Hyuktae Kwon, Jeong‑hyeon Park, Yena Kim, Jinyoung Sohn, Shinyoung Park, Hyeonhui Kim, Sun‑Kyoung Im, Yeongmin Kim, Ha Yung Chung, Myung Hee Nam, Jee Young Kwon, Il Yong Kim, Yong Jae Kim, Ji Hyeon Baek, Hak Su Kim, George M. Weinstock, Belong Cho, Charles Lee, Sungsoon Fang, Hansoo Park and Je Kyung Seong
  • Year2022
  • Sourcehttps://doi.org/10.1186/s40168-022-01374-0

Cancers - Live Biotherapeutic Lactococcus lactis GEN3013 Enhances Antitumor Efficacy of Cancer Treatment via Modulation of Cancer Progression and Immune System
  • AuthorSujeong Kim, Yunjae Kim, Suro Lee, Yulha Kim, Byungkwan Jeon, Hyerim Kim, and Hansoo Park
  • Year2022
  • Sourcehttps://doi.org/10.3390/cancers14174083

Microorganisms - Whole-Transcriptome Sequencing Reveals Characteristics of Cancer Microbiome in Korean Patients with GI Tract Cancer: Fusobacterium nucleatum as a Therapeutic Target
  • AuthorHyeok Ahn , Kyungchan Min, Eulgi Lee , Hyun Kim, Sujeong Kim, Yunjae Kim, Gihyeon Kim , Beomki Cho, Chanyeong Jeong, Yeongmin Kim and Hansoo Park
  • Year2022
  • Sourcehttps://doi.org/10.3390/ microorganisms10101896

Biomedicines - Bacteria for Treatment: Microbiome in Bladder Cancer
  • AuthorKyungchan Min, Hyun Tae Kim, Eun Hye Lee, Hansoo Park, and Yun-Sok Ha
  • Year2022
  • Sourcehttps://doi.org/10.3390/ biomedicines10081783

Int. J. Mol. Sci. - Potential Therapeutic Skin Microbiomes Suppressing Staphylococcus aureus-Derived Immune Responses and Upregulating Skin Barrier Function-Related Genes via the AhR Signaling Pathway
  • AuthorEulgi Lee, Kyungchan Min, Hyeok Ahn, Bu-nam Jeon, Shinyoung Park, Changhee Yun, Hyehee Jeon, Jae-sung Yeon, Hyun Kim and Hansoo Park
  • Year2022
  • Sourcehttps://doi.org/10.3390/ijms23179551

Probiotics Antimicrob Proteins. - Staphylococcus epidermidis WF2R11 Suppresses PM(2.5)-Mediated Activation of the Aryl Hydrocarbon Receptor in HaCaT Keratinocytes
  • AuthorLee E, Ahn H, Park S, Kim G, Kim H, Noh MG, et al
  • Year2022
  • Sourcedoi: 10.1007/s12602-022-09922-8. PubMed PMID: 35727505; PubMed Central PMCID: PMC9474527

Diabetes Obesity & Metabolism - Integrated metagenomics and metabolomics analysis illustrates the systemic impact of the gut microbiota on host metabolism after bariatric surgery
  • AuthorYeyoung Han MSc | Gihyeon Kim MSc | Eunyong Ahn PhD | Sunhee Jung PhD | Youngae Jung PhD | Yunjae Kim BSc | Eunyoung Ha MD, PhD | Yoonseok Heo MD, PhD | Do Hyun Ryu PhD | Hansoo Park MD, PhD | Geum-Sook Hwang PhD
  • Year2022
  • Sourcedoi:10.1111/dom.14689
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