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Laboratory of Drug Discovery

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Total 189 , Page 10 / 19

Synthesis and biological evaluation of α, β-unsaturated lactones as potent immunosuppressive agents
  • AuthorSun-Mi Lee, Won-Gil Lee, Young-Chul Kim, Hyojin Ko
  • Year2011
  • SourceBioorganic & medicinal chemistry letters

Synthesis of benzo[3,4]azepino[1,2-b]isoquinolin-9-ones from 3-arylisoquinolines via ring closing metathesis and evaluation of topoisomerase I inhibitory activity, cytotoxicity and docking study
  • AuthorHue Thi My Van, Daulat Bikram Khadka, Su Hui Yang, Thanh Nguyen Le, Suk Hee Cho, Chao Zhao, Ik-Soo Lee, Youngjoo Kwon, Kyung-Tae Lee, Yong-Chul Kim, Won-Jea Cho
  • Year2011
  • SourceBioorganic & medicinal chemistry

Synthesis of pheophorbide-a conjugates with anticancer drugs as potential cancer diagnostic and therapeutic agents
  • AuthorHyun You, Hyo-Eun Yoon, Jung-Hoon Yoon, Hyojin Ko, Yong-Chul Kim
  • Year2011
  • SourceBioorganic & medicinal chemistry

Characterization of protoberberine analogs employed as novel human P2X7 receptor antagonists
  • AuthorGa Eun Lee, Won-Gil Lee, Song-Yi Lee, Cho-Rong Lee, Chul-Seung Park, Sunghoe Chang, Sung-Gyoo Park, Mi-Ryoung Song, Yong-Chul Kim
  • Year2011
  • SourceToxicology and applied pharmacology

Design, synthesis and X-ray crystallographic study of NAmPRTase inhibitors as anti-cancer agents
  • AuthorHyun You, Hyung-Seop Youn, Isak Im, Man-Ho Bae, Sang-Kook Lee, Hyojin Ko, Soo Hyun Eom, Yong-Chul Kim
  • Year2011
  • SourceEuropean journal of medicinal chemistry

Synthesis of a Multifunctional Oxazolo [5, 4-e][1, 4] diazepine Skeleton
  • AuthorGundurao Kolavi, I-Sak Im, Yong-Chul Kim, Hyo-Jin Ko
  • Year2011
  • SourceBulletin of the Korean Chemical Society

4-Chloro-7-trifluoromethyl-10H-benzo [4, 5] furo [3, 2-b] indole-1-carboxylic acid (TBIC), a putative BKCa channel opener with uterine relaxant activities
  • AuthorHyung Seok Ahn, Ike dela Peña, Yong Chul Kim, Jae Hoon Cheong
  • Year2011
  • SourcePharmacology

Risk of intravascular injection in transforaminal epidural injections
  • AuthorFS Nahm, CJ Lee, SH Lee, TH Kim, WS Sim, HS Cho, SY Park, Yong Chul Kim, SC Lee
  • Year2010
  • SourceAnaesthesia

Antimicrobial effect of photodynamic therapy using a highly pure chlorin e6
  • AuthorJong-Hwan Park, Yeon-Hee Moon, Iel-Soo Bang, Yong-Chul Kim, Soo-A Kim, Sang-Gun Ahn, Jung-Hoon Yoon
  • Year2010
  • SourceLasers in medical science

Stimulation of the P2X7 receptor kills rat retinal ganglion cells in vivo
  • AuthorHuiling Hu, Wennan Lu, Mei Zhang, Xiulan Zhang, Arthur J Argall, Shaun Patel, Ga Eun Lee, Yong-Chul Kim, Kenneth A Jacobson, Alan M Laties, Claire H Mitchell
  • Year2010
  • SourceExperimental eye research
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