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Laboratory of Drug Discovery

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Total 189 , Page 7 / 19

Discovery of Novel 2,5-Dioxoimidazolidine-Based P2X7 Receptor Antagonists as Constrained Analogues of KN62
  • AuthorJin-Hee Park, Ga-Eun Lee, So-Deok Lee, Tran Thi Hien, Sujin Kim, Jin Won Yang, Joong-Heui Cho, Hyojin Ko, Sung-Chul Lim, Yoon-Gyoon Kim, Keon-Wook Kang, Yong-Chul Kim
  • Year2015/2/23
  • SourceJournal of medicinal chemistry

RUNX3 confers sensitivity to pheophorbide a-photodynamic therapy in human oral squamous cell carcinoma cell lines
  • AuthorSook Moon, Jung Yoon Bae, Hwa-Kyung Son, Doo Young Lee, Gyeongju Park, Hyun You, Hyojin Ko, Yong-Chul Kim, Jin Kim
  • Year2015/2/1
  • SourceLasers in medical science

Structure–activity relationship studies of pyrimidine-2, 4-dione derivatives as potent P2X7 receptor antagonists
  • AuthorJin-Hee Park, Ga-Eun Lee, So-Deok Lee, Hyojin Ko, Yong-Chul Kim
  • Year2015/12/1
  • SourceEuropean journal of medicinal chemistry

5-Nitro-5′-hydroxy-indirubin-3′-oxime (AGM130), an indirubin-3′-oxime derivative, inhibits tumor growth by inducing apoptosis against non-small cell lung cancer in vitro and in vivo
  • AuthorMee-Young Ahn, Tae-Hyung Kim, Seong-Min Kwon, Hyo-Eun Yoon, Hyung-Sik Kim, Jae-Il Kim, Yong-Chul Kim, Keon-Wook Kang, Sang-Gun Ahn, Jung-Hoon Yoon
  • Year2015/11/15
  • SourceEuropean Journal of Pharmaceutical Sciences

Nanoparticle-encapsulated P2X7 receptor antagonist in a pH-sensitive polymer as a potential local drug delivery system to acidic inflammatory environments
  • AuthorSun-Mi Lee, Joong-Heui Cho, So-Deok Lee, Yong-Chul Kim
  • Year2015/10/1
  • SourceBioorganic & medicinal chemistry letters

Preparation and therapeutic evaluation of paclitaxel-conjugated low-molecular-weight chitosan nanoparticles
  • AuthorHyungjun Kim, Eunhye Lee, In-Hyun Lee, Jinju Lee, Jinjoo Kim, Sunghyun Kim, Yonghyun Lee, Daejin Kim, Minsuk Choi, Yong-Chul Kim, Sangyong Jon
  • Year2014/8/1
  • SourceMacromolecular Research

Synthesis and therapeutic evaluation of an aptide–docetaxel conjugate targeting tumor-associated fibronectin
  • AuthorHyungjun Kim, Yonghyun Lee, In-Hyun Lee, Sunghyun Kim, Daejin Kim, Phei Er Saw, Jinju Lee, Minsuk Choi, Yong-Chul Kim, Sangyong Jon
  • Year2014/3/28
  • SourceJournal of controlled release

Design, synthesis and SAR studies of novel P2X receptor antagonists
  • AuthorJin-Hee Park, Ga-Eun Lee, Joong-Heui Cho, Kwan-Young Jung, Younghwan Jung, Hyojin Ko, Chul-Seung Park, Yong-Chul Kim
  • Year2014/12/1
  • SourcePURINERGIC SIGNALLING

Solid-phase synthesis of quinolinone library
  • AuthorSeung-hwa Kwak, Min Jeong Kim, So-Deok Lee, Hyun You, Yong-Chul Kim, Hyojin Ko
  • Year2014/12/1
  • SourceACS combinatorial science

5‐Nitro‐5′ hydroxy‐indirubin‐3′ oxime Is a Novel Inducer of Somatic Cell Transdifferentiation
  • AuthorDa‐Woon Jung, Young J Hong, Soo‐Yeon Kim, Woong‐Hee Kim, Shinae Seo, Jung‐Eun Lee, Haihong Shen, Yong‐Chul Kim, Darren R Williams
  • Year2014/11
  • SourceArchiv der Pharmazie
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