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Laboratory of Drug Discovery

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Total 189 , Page 13 / 19

Bladder-relaxant properties of the novel benzofuroindole analogue LDD175
  • AuthorIke Campomayor dela Peña, Seo Young Yoon, Sung Mok Kim, Geum Seon Lee, Jong Hoon Ryu, Chul-Seung Park, Yong Chul Kim, Jae Hoon Cheong
  • Year2009
  • SourcePharmacology

Indirubin-3′-monoxime, a derivative of a Chinese anti-leukemia medicine, inhibits Notch1 signaling
  • AuthorMi-Jee Lee, Mi-Yeon Kim, Jung-Soon Mo, Eun-Jung Ann, Mi-Sun Seo, Ji-Ae Hong, Yong-Chul Kim, Hee-Sae Park
  • Year2008
  • SourceCancer letters

Synthesis and structure–activity relationship studies of tyrosine-based antagonists at the human P2X7 receptor
  • AuthorGa Eun Lee, Bhalchandra V Joshi, Wangzhong Chen, Lak Shin Jeong, Hyung Ryong Moon, Kenneth A Jacobson, Yong-Chul Kim
  • Year2008
  • SourceBioorganic & medicinal chemistry letters

Molecular Mechanisms of Neurologic Disorders (Neurobiology): Indirubin-3-monoxime, a derivative of a Chinese antileukemia medicine, inhibits Notch1 signaling
  • AuthorSeo Mi Sun, Mi Jee Lee, Mi Yeon Kim, Jung Soon Mo, Eun Jung Ann, Ji Ae Hong, Yong Chul Kim, Hee Sae Park
  • Year2008
  • Source생화학분자생물학회 춘계학술발표논문집

Structure−Activity Relationship Studies of Spinorphin as a Potent and Selective Human P2X3 Receptor Antagonist
  • AuthorKwan-Young Jung, Hyoun Duk Moon, Ga Eun Lee, Hyun-Ho Lim, Chul-Seung Park, Yong-Chul Kim
  • Year2007
  • SourceJournal of medicinal chemistry

Development of potent inhibitors of the coxsackievirus 3C protease
  • AuthorEui Seung Lee, Won Gil Lee, Soo-Hyeon Yun, Seong Hwan Rho, Isak Im, Sung Tae Yang, Saravanan Sellamuthu, Yong Jae Lee, Sun Jae Kwon, Ohkmae K Park, Eun-Seok Jeon, Woo Jin Park, Yong-Chul Kim
  • Year2007
  • SourceBiochemical and biophysical research communications

Antitumor activity of novel indirubin derivatives in rat tumor model
  • AuthorSoo-A Kim, Yong-Chul Kim, Si-Wouk Kim, Sang-Ho Lee, Jung-Joon Min, Sang-Gun Ahn, Jung-Hoon Yoon
  • Year2007
  • SourceClinical cancer research

Enhancing effect of indirubin derivatives on 1, 25-dihydroxyvitamin D3-and all-trans retinoic acid-induced differentiation of HL-60 leukemia cells
  • AuthorSeung Hyun Kim, Si-Wouk Kim, Soo Jeong Choi, Yong-Chul Kim, Tae Sung Kim
  • Year2006
  • SourceBioorganic & medicinal chemistry

Establishment of an Assay for P2X7 Receptor-Mediated Cell Death.
  • AuthorSong-Yi Lee, Sooyeon Jo, Ga Eun Lee, Lak Shin Jeong, Yong-Chul Kim, Chul-Seung Park
  • Year2006
  • SourceMolecules & Cells (Springer Science & Business Media BV)

Electrophysiological characterization of benzofuroindole-induced potentiation of large-conductance Ca2+-activated K+ channels
  • AuthorTal Soo Ha, Hyun-Ho Lim, Ga Eun Lee, Yong-Chul Kim, Chul-Seung Park
  • Year2006
  • SourceMolecular pharmacology
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