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Laboratory of Drug Discovery

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Total 189 , Page 15 / 19

Structure–activity relationships of thiazole and thiadiazole derivatives as potent and selective human adenosine A3 receptor antagonists
  • AuthorKwan-Young Jung, Soo-Kyung Kim, Zhan-Guo Gao, Ariel S Gross, Neli Melman, Kenneth A Jacobson, Yong-Chul Kim
  • Year2004
  • SourceBioorganic & medicinal chemistry

Application of a novel design paradigm to generate general nonpeptide combinatorial scaffolds mimicking beta turns: synthesis of ligands for somatostatin receptors
  • AuthorDona Chianelli, Yong-Chul Kim, Dmitriy Lvovskiy, Thomas R Webb
  • Year2003
  • SourceBioorganic & medicinal chemistry

N6-Substituted D-4‘-Thioadenosine-5‘-methyluronamides:  Potent and Selective Agonists at the Human A3 Adenosine Receptor
  • AuthorLak Shin Jeong, Dong Zhe Jin, Hea Ok Kim, Dae Hong Shin, Hyung Ryong Moon, Prashantha Gunaga, Moon Woo Chun, Yong-Chul Kim, Neli Melman, Zhan-Guo Gao, Kenneth A Jacobson
  • Year2003
  • SourceJournal of medicinal chemistry

A novel flavin-containing monooxygenase from Methylophaga sp. strain SK1 and its indigo synthesis in Escherichia coli
  • AuthorHack Sun Choi, Jin Kwon Kim, Eun Hee Cho, Yong Chul Kim, Jae Il Kim, Si Wouk Kim
  • Year2003
  • SourceBiochemical and biophysical research communications

Selective cytotoxicity following Arg‐to‐Lys substitution in tritrpticin adopting a unique amphipathic turn structure
  • AuthorSung-Tae Yang, Song Yub Shin, Chul Won Lee, Yong-Chul Kim, Kyung-Soo Hahm, Jae Il Kim
  • Year2003
  • SourceFEBS letters

Synthetic Lead Compounds Modulate Activity of Large-conductance -activated Potassium Channels Expressed in Xenopus Oocytes
  • AuthorTal-Soo Ha, Yong-Chul Kim, Chul-Seung Park
  • Year2003
  • SourceProceedings of the Korean Biophysical Society Conference

Evidence for the recognition of non‐nucleotide antagonists within the transmembrane domains of the human P2Y1 receptor
  • AuthorDanping Guo, Ivar von Kügelgen, Stefano Moro, Yong‐Chul Kim, Kenneth A Jacobson
  • Year2002
  • SourceDrug development research

Conformation-dependent antibiotic activity of tritrpticin, a cathelicidin-derived antimicrobial peptide
  • AuthorSung-Tae Yang, Song Yub Shin, Yong-Chul Kim, Yangmee Kim, Kyung-Soo Hahm, Jae Il Kim
  • Year2002
  • SourceBiochemical and biophysical research communications

Actions of a series of PPADS analogs at P2X1 and P2X3 receptors
  • AuthorSean G Brown, Yong‐Chul Kim, Soon‐Ai Kim, Kenneth A Jacobson, Geoffrey Burnstock, Brian F King
  • Year2001
  • SourceDrug development research

Ribose modified nucleosides and nucleotides as ligands for purine receptors
  • AuthorKA Jacobson, RG Ravi, E Nandanan, HS Kim, S Moro, YC Kim, K Lee, D Barak, VE Marquez, XD Ji
  • Year2001
  • SourceNucleosides, Nucleotides and Nucleic Acids
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