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Laboratory of Drug Discovery

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Total 189 , Page 17 / 19

Acyclic Analogues of Deoxyadenosine 3‘,5‘-Bisphosphates as P2Y1 Receptor Antagonists
  • AuthorYong-Chul Kim, Carola Gallo-Rodriguez, Soo-Yeon Jang, Erathodiyil Nandanan, Mary Adams, T Kendall Harden, José L Boyer, Kenneth A Jacobson
  • Year2000
  • SourceJournal of medicinal chemistry

MOLECULAR-BIOLOGICAL PROBLEMS OF DRUG DESIGN AND MECHANISM OF DRUG ACTION-Effect of New Pyridoxal Phosphate Arylazo Derivatives on the Ecto-Atpase Activity in Guinea Pig Tissues
  • AuthorAU Ziganshin, AP Zaitset, IP Zaitseva, Yu Ch Kim, E Camaioni, G Burnstock, KA Jacobson
  • Year2000
  • SourcePharmaceutical Chemistry Journal

Structure activity relationships of pyridoxal phosphate derivatives as potent and selective antagonists of P2X1 receptors.
  • AuthorKA Jacobson, SG Brown, TK Harden, JL Boyer, GR Dubyak, BF King, G Burnstock, YC Kim
  • Year2000
  • SourceDrug Development Research

Versatile synthesis of 6-alkyl and aryl substituted pyridoxal derivatives
  • AuthorYong-Chul Kim, Kenneth A Jacobson
  • Year2000
  • SourceSynthesis

Acyl‐hydrazide derivatives of a xanthine carboxylic congener (XCC) as selective antagonists at human A2B adenosine receptors
  • AuthorYong‐Chul Kim, Yishai Karton, Xiao‐duo Ji, Neli Melman, Joel Linden, Kenneth A Jacobson
  • Year1999
  • SourceDrug development research

Structure−Activity Relationships of Bisphosphate Nucleotide Derivatives as P2Y1 Receptor Antagonists and Partial Agonists
  • AuthorErathodiyil Nandanan, Emidio Camaioni, Soo-Yeon Jang, Yong-Chul Kim, Gloria Cristalli, Piet Herdewijn, John A Secrist, Kamal N Tiwari, Arvind Mohanram, T Kendall Harden, José L Boyer, Kenneth A Jacobson
  • Year1999
  • SourceJournal of medicinal chemistry

Recognition of pyridoxal phosphate-related antagonists occurs with transmembrane domains of the human P2Y (1) receptor.
  • AuthorDP Guo, S Moro, I von Kugelgen, YC Kim, KA Jacobson
  • Year1999
  • SourceFASEB JOURNAL

Molecular recognition in P2 receptors: ligand development aided by molecular modeling and mutagenesis
  • AuthorKenneth A Jacobson, Carsten Hoffmann, Yong-Chul Kim, Emidio Camaioni, Erathodiyil Nandanan, Soo Yeon Jang, Dan–Ping Guo, Xiao-duo Ji, Ivar von Kügelgen, Stefano Moro, Airat U Ziganshin, Alexei Rychkov, Brian F King, Sean G Brown, Scott S Wildman, Geoffrey Burnstock, Jose L Boyer, Arvind Mohanram, T Kendall Harden
  • Year1999
  • SourceProgress in brain research

Synthesis and structure‐activity relationships of pyridoxal‐6‐arylazo‐5′‐phosphate and phosphonate derivatives as P2 receptor antagonists
  • AuthorYong‐Chul Kim, Emidio Camaioni, Airat U Ziganshin, Xiao‐duo Ji, Brian F King, Scott S Wildman, Alexei Rychkov, Joshua Yoburn, Heaok Kim, Arvind Mohanram, T Kendall Harden, José L Boyer, Geoffrey Burnstock, Kenneth A Jacobson
  • Year1998
  • SourceDrug development research

Some 6-phenylazopyridoxalphosphate derivatives influence P2-purinoreceptor-mediated effects
  • AuthorAU Ziganshin, AV Rychkov, LE Ziganshina, Yu Ch Kim, E Kamaioni, G Burnstock, KA Jacobson
  • Year1998
  • SourcePharmaceutical chemistry journal
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